| This Wk | Last Wk | Title | Distributor | Weekend Gross | Cumulative Gross | Wks Out | # of Theaters |
| 1 | | WALL-E | WALT DISNEY STUDIOS | $62,500,000 | $62,500,000 | 1 | 3992 |
| 2 | | WANTED | UNIVERSAL | $51,118,000 | $51,118,000 | 1 | 3175 |
| 3 | 1 | GET SMART | WARNER BROS. | $20,000,000 | $77,265,789 | 2 | 3915 |
| 4 | 3 | KUNG FU PANDA | PARAMOUNT | $11,746,000 | $179,330,693 | 4 | 3670 |
| 5 | 2 | THE INCREDIBLE HULK | UNIVERSAL | $9,226,000 | $115,507,965 | 3 | 3349 |
| 6 | 4 | THE LOVE GURU | PARAMOUNT | $5,440,000 | $25,321,482 | 2 | 3012 |
| 7 | 6 | INDIANA JONES AND THE KINGDOM OF THE CRYSTAL SKULL | PARAMOUNT | $5,030,000 | $299,935,487 | 6 | 2556 |
| 8 | 5 | THE HAPPENING | TWENTIETH CENTURY FOX | $3,850,000 | $59,062,906 | 3 | 2483 |
| 9 | 8 | SEX AND THE CITY | WARNER BROS. | $3,770,000 | $140,132,074 | 5 | 1755 |
| 10 | 7 | YOU DON'T MESS WITH THE ZOHAN | SONY PICTURES | $3,200,000 | $91,214,915 | 4 | 2147 |
| 11 | 9 | IRON MAN | PARAMOUNT | $2,254,000 | $309,176,205 | 9 | 1379 |
| 12 | 11 | THE CHRONICLES OF NARNIA: PRINCE CASPIAN | WALT DISNEY STUDIOS | $1,060,000 | $137,687,631 | 7 | |
